Search for your favorite variant, genomic region, or gene to browse experimental data and computational predictions from the IGVF Consortium and other data sources.
Search for a variant, region, or gene
Currently, the Catalog includes a preview of IGVF measurements and predictions, including:
- Saturation mutagenesis of coding variants in 10 genes (VAMP-seq, SGE)
- Variant effect predictions for all amino acid substitutions (MutPred2, ESM-v1)
- Enhancer-gene predictions in 1700 biosamples (ENCODE-rE2G)
- STARR-seq predictions of variant effects in (K562 cells) (BlueSTARR)
- MPRA measurements of variant effects
The IGVF Catalog also integrates information from the eQTL Catalogue, GWAS Catalog, ENCODE, and other resources. See Data Sources.
Related Apps
Other web resources to view certain IGVF data
FAVOR
View annotations for every possible single-nucleotide variant
- Feature-rich variant annotation matrix for bulk downloads.
- Matches the scoring columns surfaced in IGVF coding tables.
MaveDB
Explore MAVE experiments from IGVF and other projects
- Browse per-variant activity scores and metadata for each MAVE experiment.
- Links out to raw data, analysis notebooks, and consortium publications.
IGVF Coding Variants
Explore MAVE data from IGVF
- Search by gene or variant name to jump straight to multiplexed measurements.
- Mirrors the experimental rows you see inside IGVF variant pages.
Lipids Knowledge Portal Network
Explore functional annotations at GWAS signals for lipid traits
- Integrates IGVF measurements with lipid trait cohorts.
- Provides curated visualizations tailored to cardiometabolic phenotypes.
E2G
View enhancer-gene predictions from ENCODE, IGVF, and other projects
- Visualize biosample-specific enhancer to gene links for any locus.
- Download posterior probabilities to compare against IGVF region dashboards.
RegulomeDB
View annotations of noncoding variants from ENCODE
- Instantly scores variants using motif hits, DNase, TF binding, and QTL context.
- Great companion when triaging variants discovered through IGVF browse.
IGVF Data Portal
Primary ingestion point for raw IGVF files, processed pipelines, and metadata submissions.
- Access raw files that back the summarized tables in the catalog.
- Find submission status and harmonized metadata across the consortium.
DACC IGVF Catalog
The application you are currently using—the DACC-built catalog that links variants, genes, regions, and ontologies.
- Unified search across rsIDs, genes, regions, and publications.
- Interactive tables powered by the same APIs exposed under /api.
Explore the API
Access IGVF Consortium datasets programmatically through our comprehensive API, enabling seamless integration of genomic variation and functional data into your research workflows.
Documentation
Access detailed documentation and examples demonstrating how to query, visualize, and integrate IGVF resources. Future updates will expand use cases and API coverage.
IGVF Chatbot
The IGVF Chatbot assists users by translating natural language queries into AQL, retrieving results directly from our knowledge graph.